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Ï㽶ÊÓƵ's Faculty of Medicine and Health Sciences is the University's oldest faculty as well as the first medical faculty in Canada. Established through a merger between McGill College and the Montreal Medical Institution, the latter founded in 1823 by four staff members of the newly opened Montreal General Hospital, the Faculty began teaching activities in 1829. Four years later, in 1833, it awarded its first degree to William Leslie Logie, McGill's first graduate and the first physician trained on Canadian soil.

In 2020, the Faculty changed its name from the Faculty of Medicine to the Faculty of Medicine and Health Sciences, to better reflect its expanded scope, encompassing a range of health professions as well as population and global health and biomedical research. Today, the Faculty consists of six schools: the School of Medicine; the Ingram School of Nursing; the School of Physical and Occupational Therapy; the School of Communication Sciences and Disorders; the School of Population and Global Health; and the School of Biomedical Sciences. Also in 2020, McGill’s Campus Outaouais opened in Gatineau, offering for the first time McGill’s prestigious undergraduate medical program in French. In the same year, it launched the McGill-UQO Medical Preparatory Program in the region, together with the Faculty of Science and the Université du Québec en Outaouais (UQO). Outaouais is part of the Réseau Universitaire Intégré de Santé et Services Sociaux McGill (RUISSS McGill) and McGill postgraduate medical students (residents) have been training there since 1988.