An open solution to improving research reproducibility
Academic and industry scientists collaborate on a new method to characterize research antibodiesStructural Genomics Consortium researchers at The Neuro (Montreal Neurological Institute-Hospital) of 㽶Ƶ, in collaboration with scientists from 11 major antibody manufacturers representing approximately 80 per cent of global renewable antibody production, have developed and standardized an Open Science platform to characterize research antibodies.
Open Science project funded for $1.5M
YCharOS antibody characterization platform addresses the “reproducibility crisis” in researchAn innovative research project led by researchers at The Neuro has been awarded $1.5M by the Government of Quebec through CQDM.
YCharOS is an innovative platform led by neuroscientists Peter McPherson and Carl Laflamme that validates antibody reagents for human proteins.
At-home neurological disorder diagnosis project receives major funding
$1M grant from The Weston Family Foundation will pave the way for earlier intervention in REM sleep behaviour disorder and Parkinson’s diseaseREM sleep behaviour disorder (RBD) is an often debilitating condition that causes people to act out in their sleep, sometimes violently. What’s worse, people with the disorder often go on to develop Parkinson’s disease.
Gene therapy project receives major funding
$1.14 million from CIHR will resolve treatment roadblocks for rare brain disordersGene therapy for rare neurological disorders will move one step forward thanks to a $1.14 million grant from the Canadian Institutes of Health Research (CIHR).
Research on new stem cell models receives $2.6 million
Thomas Durcan’s project will dissect the role of microglia in degenerative conditions, to identify new therapeutic strategies for Alzheimer's treatmentAn innovative new program based at The Neuro has received $2.6 million from the CQDM and the Brain Canada Foundation.
Bilingualism makes the brain more efficient, especially when learned at a young age
MRI data from large sample shows increased whole-brain connectivity in people with a second languageNeuroplasticity is the brain’s ability to build connections within itself, adapting to the surrounding environment. The brain is most plastic in childhood, forming new pathways in reaction to stimuli such as language.
Recreating a hallmark of Parkinson's disease in human neurons
Scientists use stem cells to follow development of protein bodies characteristic of neurological diseaseLewy bodies are a hallmark of Parkinson's disease (PD) and other related neurological conditions. Understanding why and how they develop is critical to developing better treatments.
Alan Evans elected Fellow of the Royal Society
Honour is recognition for a lifetime of leading researchAlan Evans, a researcher at The Neuro, James McGill Professor of Neurology and Neurosurgery and co-director of the Ludmer Centre for Neuroinformatics and Mental Health, has been elected to the Fellowship of the Royal Society, joining a class of scientists that includes a Nobel laureate and a former Chief Medical Advisor to the US President.
Two Neuro projects funded by international partnership
Researchers will study how hormones affect brain cancer and the role of neural circuits in social skillsThe Paris Brain Institute and the Institut Pasteur have partnered with The Neuro to fund two groundbreaking studies, each receiving more than $440,000. These projects are part of an international collaboration to address future challenges in neuroscience.
$10.6M grant supports innovative autism project
McGill Translational Platform in Autism Research will help uncover the disorders’ neural foundationsA new project at The Neuro, 㽶Ƶ and the Research Institute of the 㽶Ƶ Health Centre (RI-MUHC) has been awarded $10.6M in financial support as part of the Canada Foundation for Innovation’s (CFI) Innovation Fund.
Making AI a partner in neuroscientific discovery
New paper argues that Large Language Models can reveal breakthroughs humans alone cannotThe past year has seen major advances in Large Language Models (LLMs) such as ChatGPT. The ability of these models to interpret and produce human text sources (and other sequence data) has implications for people in many areas of human activity.
A neurological disease paradigm shift
Researchers propose a new model for classifying Parkinson’sOne of the things that makes developing effective treatments for Parkinson’s disease so challenging is its complexity. While some forms are caused by genetics, others have environmental factors, and patients can show a wide range of symptoms of varying severity. Diagnosis of Parkinson’s is also currently made very late, after the disease may have been in the brain for a decade or more.
Open Science momentum grows stronger in Canada with a new commitment by its largest mental health teaching hospital
The Centre for Addiction and Mental Health (CAMH) joins the Tanenbaum Open Science Institute alliance in a partnership to open research practicesThe Centre for Addiction and Mental Health (CAMH), Canada’s largest mental health teaching hospital in the country is pleased to announce that it has entered into a partnership with the Tanenbaum Open Science Institute (TOSI) at 㽶Ƶ
Assessing unintended consequences in AI-based neurosurgical training
Machine learning tutors affect learners in unforeseen ways, both positive and negativeVirtual reality simulators can help learners improve their technical skills faster and with no risk to patients. In the field of neurosurgery, they allow medical students to practice complex operations before using a scalpel on a real patient.
Neuro researchers receive more than $3.6M in CIHR funding
Projects will discover disease genetics, explain cognition/memory formation, improve surgical accuracy and post-concussion diagnosisFive Neuro-led projects were awarded grants by the Canadian Institutes of Health Research (CIHR) this year as part of its spring funding, totaling more than $3.6M.