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The Killam Seminar Series presents:听Are we ready for PD prevention studies : PPMI experience

Tanya Simuni

Arthur C. Nielsen Professor of Neurology

Division Head, Parkinson's disease and Movement Disorders Center

Northwestern University Feinberg School of Medicine

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Abstract: The Parkinson鈥檚 disease (PD) research field has seen exponential advancement in the deeper understanding of the clinical features of the disease from the earliest stages of pathology all the way to manifest disease, identification of large prodromal cohorts coupled with promising in vivo biomarkers. All these advances enable to start planning disease prevention studies. This talk will summarize design of the Path to Prevention (P2P) study planned by the MJFF. The talk will review the key aspects of target population selection, focusing on the staged biological characterization of the participants, and statistical consideration for the study design.

Bio:听Dr. Simuni joined the faculty of the Northwestern University Feinberg School of Medicine in 2000 to build a multidisciplinary movement disorders center that is recognized by the Parkinson鈥檚 Foundation, Huntington Disease Society of America and Wilson鈥檚 Foundation as a Center of Excellence and serves as a training model in the region. She is the lead investigator of a number of clinical trials on experimental pharmacology, non-motor manifestations, and pharmacological management of PD. She serves on a number of Steering Committees for the PD national clinical trials, several committees for PSG and the PF. She is the Site PI and Steering Committee member for the largest PD biomarker initiative (PPMI study) and site PI for the Network for Excellence in Neuroscience Clinical Trials (NEXT). Dr. Simuni is an active member of the American Academy of Neurology, American Neurological Association, the Movement Disorders Society as well as the Parkinson鈥檚 Study Group.

Supported by the generosity of the Killam Trusts, the MNI's Killam Seminar Series invites outstanding guest speakers whose research is of interest to the scientific community at the MNI and 香蕉视频.