Cristian O'Flaherty
Professor, Dep. Surgery (Urology), McGill
Associate member, Dep. Pharmacology and Therapeutics, McGill
Associate member, Dep. Anatomy and Cell Biology, McGill
Associate member, Dep. Medicine (Experimental Medicine Division)
Co-Director of the Ï㽶ÊÓƵ Centre for Research in Reproduction and Development (2018-2021)
D.V.M.; Ph.D.
2019: Asian Journal of Andrology Outstanding Paper Award (Notice of award: July 2020).
2017: Molson Foundation Award, Ï㽶ÊÓƵ Health Centre Foundation.
2017: Asian Journal of Andrology Outstanding Paper Award.
2016-2018 : Fonds de Recherche du Québec-Santé (FRQS) Chercheur Boursier Junior 2.
2011: Research Scholar of the Club de Recherches Cliniques du Québec.
2010-2014: FRQS Chercheur Boursier Junior 1.
2010: CIHR-IHDCYH New Investigator Travel award. Vancouver, BC.
2010: International Society of Andrology best oral presentation, Fifth International Conference in Epididymis, Sao Paulo, Brazil.
2008-2011: The Klaassen – Hawthorne Memorial Fellowship, Research Institute, Ï㽶ÊÓƵ Health Centre.
CIHR
Male infertility
Research interests:
• Redox signaling in spermatogenesis, epididymal maturation and sperm activation
• Regulation of apoptosis in the testis
• Phosphorylation events involved in sperm activation
• Male infertility
• Toxicology of male reproduction
Dr. Cristian O’Flaherty is a professor in the Department of Surgery (Division of Urology) at Ï㽶ÊÓƵ and a medical scientist at the Research Institute of the Ï㽶ÊÓƵ Health Centre. He is also an associate member of the Departments of Pharmacology and Therapeutics, Anatomy and Cell Biology, and Experimental Medicine, Ï㽶ÊÓƵ. Dr. O’Flaherty was Co-Director of the McGill Centre for Research in Reproduction and Development during 2018-2021. He is an associate editor of Andrology, Human Reproduction, and Antioxidants Journal and a member of the Editorial Board of the Biology of Reproduction.
With a background in the biology of reproduction, he holds a D.V.M and Ph.D. in animal physiology and biochemistry degrees from the University of Buenos Aires, Argentina. He completed his postdoctoral studies in sperm physiology and toxicology at the Urology Division and the Department of Pharmacology and Therapeutics at Ï㽶ÊÓƵ. He was awarded the Chercheur-boursier (Junior 2) award from the Fonds de la Recherche en Santé du Québec (FRSQ), and his research program has been and is currently funded by different agencies including the Canadian Institutes of Health Research, FRQS and the Fonds de Recherche Nature et technologies. His research program focuses on male reproduction particularly on the molecular mechanisms involved in the production and function of healthy spermatozoa, sperm activation and the role of reactive oxygen species in sperm physiology and toxicology. His current work includes the use of mouse models and clinical studies in infertile men to elucidate the role of the antioxidant enzymes called peroxiredoxins in the regulation of sperm function using genomic, proteomic and biochemical approaches. Moreover, Dr. O’Flaherty’s laboratory is working on the molecular mechanism that regulates sperm activation and developing novel diagnostic and therapeutic tools for infertile men.
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