Overview
BIEN : Basic principles of cell culture engineering, cell line development and cell culture products; genomics, proteomics and post-translational modifications; elements of cell physiology for medium design and bioprocessing; bioreactor design, scale-up for animal cell culture and single use equipment; challenges in downstream processing of cell-culture derived products; process intensification: fed-batch, feeding strategies and continuous manufacturing; scale-down and process modeling; Process Analytical technologies and Quality by Design (QbD) concept.
Terms: Fall 2024, Winter 2025
Instructors: Jardon, Mario (Fall) Jardon, Mario; Kamen, Amine (Winter)
(3-0-6)
Prerequisite: Permission of instructor.