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Childhood trauma increases risk of chronic pain in adulthood

Published: 20 December 2023

Physical, sexual, or emotional abuse, or neglect, either alone or combined with other types of childhood trauma, increases the risk of chronic pain and related disability in adulthood, according to...

A new model to identify and predict chronic pain

Published: 20 July 2023

Chronic pain is a complex condition that affects millions of individuals worldwide and understanding its causes and predicting its trajectory remains difficult. However, findings from a recent...

No pain, no gain? How the brain chooses between pain and profit

Published: 20 July 2022

Imagine having to choose over and over between what you enjoy doing and the pain that it might cause you, whether physical or emotional. If you live with conditions such as depression, anxiety, or...

Sex bias in pain research

Published: 21 May 2020

It is increasingly clear that male and female humans and rodents process pain in different ways. And that there are important differences in the underlying mechanisms involved at genetic, molecular...

Pain-induced changes in the brain’s opioid system may explain the limited effectiveness of opioid therapy in chronic pain

Published: 27 May 2018

Pain-induced changes in the brain’s opioid receptor system may explain the limited effectiveness of opioid therapy in chronic pain and may play a role in the depression that often accompanies it,...

Newly discovered pathway for pain processing could lead to new treatments

Published: 8 August 2017

The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at...

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