It is increasingly clear that male and female humans and rodents process pain in different ways. And that there are important differences in the underlying mechanisms involved at genetic, molecular...
Mice represent well over half of the non-human subjects of biomedical research, and the vast majority of those mice are inbred. Formed by generation after generation of mating between brothers and...
The discovery of a new biological pathway involved in pain processing offers hope of using existing cancer drugs to replace the use of opioids in chronic pain treatment, according to scientists at...
There is a placebo effect for both the patient who receives a placebo and the one who receives a real drug, according to Jeffrey Mogil, a professor in the department of psychology at McGill...
November 19 marks the 50th anniversary of the ground-breaking paper, “Pain Mechanisms: A New Theory” co-authored by McGill’s Ronald Melzack, and the late Patrick Wall, which introduced gate-control...
A new study finds that rising placebo responses may play a part in the increasingly high failure rate for clinical trials of drugs designed to control chronic pain caused by nerve damage.