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McGill's Montreal Neurological Institute conducted a study using MRI imaging looking at brain activity. They found that MRI results of those athletes who had suffered from concussions had similar patterns of brain activity as people with major depressive disorder.

They concluded that those who had no previous history of depression, after a concussion - had a higher risk of becoming depressed. Interestingly, they noted that there were actual changes in the anatomy of the brain after concussion that made an injured brain look like a depressed brain.