Richard B. Richardson
Adjunct Professor, Medical Physics Unit, Ï㽶ÊÓƵ
Principal Scientist & Dosimetry Section Leader,
Radiological Protection Research & Instrumentation, Canadian Nuclear Laboratories (CNL)
PhD, Physics (Bristol '92)
Improving treatments for leukemia at Ottawa Hospital by understanding radiation effects on mitochondria and stem cells.
Neutron quality factors, mitochondrial effects in cancer/aging, radiation-induced cataracts, radon biomarkers
PATERSON, L. C., FESTARINI, A., STUART, M., ALI, F., COSTELLO, C., BOYER, C., ROGGE, R., YBARRA, N., KILDEA, J. & RICHARDSON, R. B. 2022. High-accuracy relative biological effectiveness values following low-dose thermal neutron exposures support bimodal quality factor response with neutron energy. Int J Mol Sci, 23.
RICHARDSON, R.B., ANGHEL, C.V., DENG, D.S. 2021. Profound synchrony of age-specific incidence rates and tumor suppression for different cancer types as revealed by the multistage-senescence model of carcinogenesis. Aging (Albany NY), 13(20),23545-23578.
PATERSON, L. C., YONKEU, A., ALI, F., PRIEST, N. D., BOREHAM, D. R., SEYMOUR, C. B., NORTON, F., & RICHARDSON, R. B. 2021. Relative biological effectiveness and non-Poissonian distribution of dicentric chromosome aberrations following Californium-252 neutron exposures of human peripheral blood lymphocytes. Radiat Res, 195(2), 211-217.
PATTEN, D. A., MCGUIRK, S., ANILKUMAR, U., ANTOUN, G., GANDHI, K., PARMAR, G., IQBAL, M. A., WONG, J., RICHARDSON, R. B., ST-PIERRE, J., SLACK, R. S., & HARPER, M. E. 2021. Altered mitochondrial fusion drives defensive glutathione synthesis in cells able to switch to glycolytic ATP production. Biochim Biophys Acta Mol Cell Res, 1868(1), 118854.
RICHARDSON, R. B., AINSBURY, E. A., PRESCOTT, C. R., & LOVICU, F. J. 2020. Etiology of posterior subcapsular cataracts based on a review of risk factors including aging, diabetes, and ionizing radiation. Int J Radiat Biol, 96(11), 1339-1361.
PATTEN, D. A., OUELLET, M., ALLAN, D. S., GERMAIN, M., BAIRD, S. D., HARPER, M. E. & RICHARDSON, R. B. 2019. Mitochondrial adaptation in human mesenchymal stem cells following ionizing radiation. FASEB J, 33(8), 9263-9278.
HAN, C. Y., PATTEN, D. A., RICHARDSON, R. B., HARPER, M. E. & TSANG, B. K. 2018. Tumor metabolism regulating chemosensitivity in ovarian cancer. Genes Cancer, 9, 155-175.
ALI, F., ATANACKOVIC, J., BOYER, C., FESTARINI, A., KILDEA, J., PATERSON, L. C., ROGGE, R., STUART, M. & RICHARDSON, R. B. 2018. Dosimetric and microdosimetric analyses for blood exposed to reactor-derived thermal neutrons. J Radiol Prot, 38, 1037-1052.
Radiation Protection Advisor, HPA Certification, United Kingdom (1987)