âIâm a psychologist,â said Dana Small (MScAâ98, PhDâ01). âMy interest is behaviour and brain relationships. In a way, though, I guess Iâm a wayward psychologist because I got into metabolism. One thing has led to another.â
Prof. Small was talking last month in an office at The Neuro (Montreal Neurological Institute-Hospital) that sheâs been using since being chosen for the Canadian Excellence Research Chair in Brain and Metabolism, a prestigious position that has brought her back to the city of her postgraduate years after two decades at Yale. Itâs a cozy nook with enough space for a computer desk, a small table, and her e-bike, which she prefers not to leave outside. She had just returned from a two-day conference in Copenhagen on precision nutrition, a detail that offers a handy indication as to how far she has ranged beyond the standard psychologistâs remit. Hers has indeed been an uncommonly circuitous route, one in which food and metabolism loom large. More of which later.
Smallâs story starts on Vancouver Island, where she grew up the only child of a single mother who had epilepsy. Not only was it a situation that engendered a serious sense of responsibility in her at an early age, but it set her on the path she follows to this day.
âWhen I was 11,â she said, âI wrote a time capsule that said, âI want to be a brain scientist.â That was because of my mom. I would see her lose her consciousness with seizures. I also saw her change with seizure medication. Thatâs what really drove my interest in the brain. How could she be conscious one minute and not conscious the next? What was going on there? From that time, my holy grail as a scientist has been to understand consciousness.â
The opportunity to put that mission into practice had to wait. First came a youthful adventure that saw the aspiring musician make a leap of faith and move to Montreal. It was to prove a fateful choice.
âI drove across the country with my cat and worldly possessions in a little Toyota Tercel,â she recalled. âMy plans were vague but included taking creative writing courses at Concordia and playing flamenco guitar.â
Arriving in the low-rent early 1990s, an era when the day-at-a-time bohemian lifestyle was still possible, Small found herself falling in love with the city and with francophone culture. She quickly became a habituĂ©e of the cityâs independent music scene, busking on Prince Arthur Street, getting to know future stars Rufus Wainwright and Lhasa de Sela, and writing a music column for the magazine Image (now long defunct). Soon enough, though, a reckoning came.
âThatâs right,â she said with a chuckle. âOnce in a great while I managed to find a music gig that paid. But I got hungry, literally, because I wasnât good enough. It was time to come up with a career path.â
To keep a toehold in the science world, Small had volunteered as a research assistant in an animal lab in the psychology department at Concordia. A short-lived idea to combine teaching with travel ended when, through a serendipitous series of events, she met Marilyn Jones-Gotman (MAâ71, PhDâ75), a professor in the Department of Neurology and Neurosurgery working on epilepsy, who was to become her McGill doctoral advisor and mentor.
Fast forward, beyond the PhD and several years at Yale, and Small was grappling with whether to sign on with the Max Planck Institute in Munichâthey had cold-called her during the pandemic asking if she wanted to be a directorâwhen the possibility of the Canada Excellence Research Chair (CERC) came up.
âI loved Yale,â Small stressed. âI had a great time there. My husband (astrophysicist Pieter Van Dokkum) is still on the faculty there, my stepdaughter is an undergraduate there. But the idea of coming back to Canada was always in my mind. CERC meant I could have a whole lot of new opportunities and I could do it at home.â
One of those opportunities, in fact, the chief focus of Smallâs CERC time hitherto, involves the metabolism portion of her brain-and-metabolism research.
âObesity is now the number one risk factor for dementia, apart from age,â she said. âThe food environment, and being obese, are somehow damaging the brain. Itâs going to take a concerted effort to change this, but I do have hope, I do see traction.â
As it happens, some of Smallâs thoughts on food and the food environment are currently reaching a global audience. She appears in the new theatrically released documentary feature , a sequel to the Oscar-nominated 2008 Robert Kenner film.
âIâm in it for about fifteen minutes. My son thinks itâs super cool,â she said with a smile.
A seminal and entirely unanticipated event in Smallâs life came in 2017 when, in the course of a routine checkup while she was visiting Montreal, it was discovered that she had thyroid cancer; surgery was performed at Yale in early 2018. The procedure was successful, although it has had lasting after-effects.
âPrior to the surgery I functioned very well on five to six hours of sleep per night,â she said. âI was a workaholic. I ran, on average, about forty miles a week. Afterwards, I have needed anywhere between eight and fourteen hours of sleep, and titrating the thyroid medicine to optimize sleep has been an ongoing ordeal. Finding the energy to run has also been hard. Iâm lucky if I run ten miles per week. Needless to say, I miss my thyroid.â
Does the change have day-to-day implications for her work capacity?
âI deal with time management by listening to my own rhythms,â she said. âI work when Iâm in the groove and I stop when Iâm not. Very few professions allow you to do that, so Iâm aware of how fortunate I am. If I had to do the same amount of work, but between nine and five... I donât think I could do it.â
Asked if sheâs someone whose work is portableâif sheâs a laptop cafĂ© person, for exampleâSmall replied with a different take on the very definition of work.
âI work when Iâm getting my hair done, I work on the metro. I can work almost any time and any place, and I do. Long walks and long runs are when I get the best ideas. So, ironically, you could say I do my best work when Iâm not working. Do I carry a pen and a notebook? No. If itâs worth remembering, Iâll remember it.â
Talking to someone whoâs back in Canada after an anticipated two-year stay in the United States stretched to twenty-plus, itâs hard not to ask what salient differences between living and working in the U.S. and here Small may have noted.
âIâve spent twenty years thinking about that question, and this one: what is the difference between Canadians and Americans? I think itâs down to the fact that, in Canada, youâre told, and you have the feeling, that you are entitled to health and the basics you need to survive, and you can do whatever you want on top of that. In the U.S., you have to work for all those basic things. So Americans are much more competitive. Thereâs a feeling of insecurity there, and that makes people more focused on making sure they get what they need.â
Presently halfway through the first year of her eight-year CERC tenure, Small is relishing the self-directed freedom and flexibility the position affords her. Itâs clear the chance to prioritize her scientific calling is something she intends to make the most of. A hint of her zeal ends up being revealed when sheâs asked to name a favourite piece of music, a favourite book, and a hero from history.
âMusic? Anything by . I get goosebumps just thinking about her songs. I also have to mention Paco de Lucia, the flamenco guitarist. As for a favourite book, I love Russian literature, so Iâll say Pale Fire by Nabokov. And if I could go back in time and talk to one person, it would be da Vinci. I like bicycles, and I also really appreciate the fact that he was interested in human biology and how things work.â
A kindred spirit in arts-and-science affinity, then?
âYes, thatâs it. I actually conceive of science and the arts as very similar. The fundamental thing behind each of them is the same, and thatâs discovery. Itâs just in different domains. The things that I love about science I find beautiful and profound. The reason I do it is because the feeling of discovery, of knowing something for the first time ever, is like nothing else. It doesnât happen often, but those moments sustain you.â