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Dr. Adam Shapiro

Academic title(s): 

Associate Professor, Pediatrics and Internal Medicine
Associate Member, Department of Medicine

Contact Information
Address: 

Montreal Children’s Hospital
1001 Decarie Blvd, Montreal, QC H4A 3J1

Email address: 
adam.shapiro1 [at] mcgill.ca
Alternate email address: 
adam.shapiro [at] muhc.mcgill.ca
Link(s): 
Current research: 

My research program uses in-depth clinical evaluation with deep respiratory phenotyping, including nasal nitric oxide analysis unique to my laboratory, and advanced genetic sequencing, to identify and clinically characterize new genetic variants underlying chronic suppurative lung disease and Primary Ciliary Dyskinesia in Québec.

Projects: 
  1. Hydrocephalus in Primary Ciliary Dyskinesia – To explore if PCD patients with a variety of different genetic causes have subtle CNS ventricle enlargement due to ependymal ciliary dysfunction, which may explain their increased rates of mental health disease.
  2. Primary Ciliary Dyskinesia and other mendelian causes of bronchiectasis in Canadian Inuit – Genetic exploration of various causes of chronic respiratory disease in Inuit children and adults from Northern Quebec.
  3. Splicing variants in Primary Ciliary Dyskinesia result in milder phenotypes – exploring the clinical phenotypes and outcomes in loss of function versus splicing variants in Canadian PCD cases
Selected publications: 

Research areas: 
Genetic diseases
Respiratory diseases
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