We are all familiar with the drawbacks of dehydration, but we rarely hear about the harmful effects of overhydration. It is known that excess fluid accumulation can lead to dangerously low sodium levels in the blood or hyponatremia 鈥 a life-threatening condition that can result in brain swelling. Similarly, more is known about the mechanisms in the body that detect and drive thirst while little is known about how the brain detects a state of overhydration.
A new method for projecting how the temperature will respond to human impacts supports the outlook for substantial global warming throughout this century 鈥 but also indicates that, in many regions, warming patterns are likely to vary significantly from those estimated by widely used computer models.
A team of researchers believe that Quebec鈥檚 protected areas are poised to become biodiversity refuges of continental importance. They used ecological niche modeling to calculate potential changes in the presence of 529 species in about 1/3 of the protected areas in southern Quebec almost all of which were under 50 km2 in size. Their results suggest that fifty - eighty years from now (between 2071鈥2100) close to half of the protected regions of southern Quebec may see a species turnover of greater than 80 %.
Historically, our view of host defense against infection was that we must eliminate pathogens to eradicate disease. However, this perspective has recently been challenged as scientists have taken a lesson from plant biologists about an ancient strategy involving the ability to 鈥渢olerate鈥 rather than 鈥渞esist鈥 infection to maintain health. This concept, referred to as 鈥渄isease tolerance鈥, provides an opportunity to develop new strategies that mitigate the consequences of infection.
Dr. Claudio Cuello, Professor and inaugural Charles E. Frosst/Merck endowed Chair in Pharmacology at 香蕉视频鈥檚 Faculty of Medicine is among a group of 48 leading biomedical and health scientists whose work is being recognized with election to the prestigious British Academy of Medical Sciences, announced on May 10.听 The new Fellows have been elected for their outstanding contributions to biomedical and health science, leading research discoveries, and translating developments into benefits for patients and the wider society.
Have you ever considered that working night shifts may, in the long run, have an impact on your health? A team of researchers from the 香蕉视频 affiliated Douglas Mental Health University Institute (DMHUI) has discovered that genes regulating important biological processes are incapable of adapting to new sleeping and eating patterns and that most of them stay tuned to their daytime biological clock rhythms.
The discovery of a new mechanism involved in depression 鈥 and a way to target it with a drug as effective as classical antidepressants -- provides new understanding of this illness and could pave the way for treatments with fewer side effects.
By Meaghan Thurston
New chair holder Sarah Harrison, who holds joint appointments in the Departments of Mathematics and Statistics, and Physics, will continue her investigations in string theory, a theoretical framework that proposes a unified description of all particles and forces in nature, including gravity. Among the questions Professor Harrison explores, the mysterious relationship in mathematics between finite groups and modular forms (ominously named 鈥渕onstrous moonshine鈥), which appears to have deep connections to physics and string theory.
The NEOMED Institute announced today that it has entered into a development collaboration with 香蕉视频. Kemal Payza, Senior Project Director at NEOMED Institute will collaborate with Professor Alain Nepveu, Professor at the Goodman Cancer Research Centre and Departments of Oncology, Biochemistry and Medicine at 香蕉视频, to discover new therapeutic small molecules to inhibit the protein target, Cut-Like Homeobox 1 (CUX1).
New study underlines importance of early screening and antiretroviral therapy
While the human immunodeficiency virus (HIV) has largely dropped from news headlines since the 1990s, at the end of 2016 there were 36.7 million people living with the infection, and of those only 53 per cent had access to treatment. A new study underscores the neurological consequences of exposure to HIV without antiretroviral therapy.
A $5-million gift from McGillians G. Garvin Brown IV, BA鈥91, and his wife Steffanie Diamond Brown, will make a major contribution to research and teaching at McGill鈥檚 Max Bell School of Public Policy by establishing an endowed Chair in Democratic Studies. The Chair will promote further scholarship and public outreach, encourage public discussion of key challenges facing the world鈥檚 democracies, and contribute to evidence-based policy decision-making.
By Meaghan Thurston