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Researchers find clue to rare genetic disorder

Leber hereditary optic neuropathy (LHON) is an inherited form of vision loss that causes people to have trouble with their colour vision and difficulty seeing in the centre of their visual field. Due to the founder effect from the filles du roi, there is a disproportionate preponderance of a particular LHON mutation among the French-Canadian population.

Classified as: ophthalmology
Published on: 22 May 2019

Scientists at the University of Montreal and Ï㽶ÊÓƵ have pioneered and tested a new genomic methodology which reveals a complex bacterial ecosystem at work on the International Space Station.

Until now, relatively little was known about the different types of microbes found on the space station. The new approach enables researchers to identify and map different species inside the ISS, which will ultimately help safeguard astronauts’ health and be key to future long-term space travel.

Classified as: space, International Space Station, science and technology, genomes, bacteria, Microbiology
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Published on: 22 May 2019

For most people, the influenza A virus (IAV), commonly known as the flu, is cleared from the body by our own immune system. In some cases, however, the immune response becomes dysregulated and if left uncontrolled, the inflammation caused by our own immune cells can lead to extensive lung tissue damage and enhanced morbidity and mortality.

How can we help our immune system to balance the two main host defense strategies: attacking pathogens (called host resistance) and preserving our own tissue (called disease tolerance)?

Classified as: influenza, host resistance, Maziar Divangahi, RI-MUHC, Erwan Pernet
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Published on: 22 May 2019

Today, the Honourable Kirsty Duncan, Minister of Science and Sport, announced an investment of more than $588 million through the Nearly $35 million of this investment will go to 128 McGill-led projects. McGill’s early career researchers, those who have held an independent academic position for 5 years or less, lead thirty of these projects.

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Published on: 21 May 2019

Elwyn was a healthy 13 month-old toddler when she started drinking water from the bathtub. Over time, she became increasingly thirsty and demanded more and more breast milk. For her parents, this seemed like typical behaviour related to a growth spurt. One day, however, they noticed that she was abnormally weak and rushed her to the emergency department. She was diagnosed with type 1 diabetes and had already developed a life-threatening complication of the disease known as diabetic ketoacidosis.

Classified as: Ï㽶ÊÓƵ Health Centre (RI-MUHC), health and lifestyle, faculty of medicine, type 1 diabetes, Montreal Children's Hospital, Dr. Meranda Nakhla, Child Health and Human Development Program, Diabetic ketoacidosis, Dr. Marie-Ève Robinson, science and technology
Published on: 14 May 2019

Many studies indicating that DNA nanostructures can enter cells more readily than simple DNA strands are flawed, according to researchers at Ï㽶ÊÓƵ. In a paper published in the American Chemical Society journal ACS Central Science, the McGill scientists demonstrate that many DNA cage nanostructures aren’t taken up by cells to a significant extent.

Classified as: DNA nanostructures, drug delivery, Hanadi Sleiman, Aurélie Lacroix
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Published on: 10 May 2019

Study could lead to development of personalized biomarkers and treatment

Individuals with autism spectrum disorder (ASD) are often lumped into a single catch-all group, despite significant differences in symptom profile and severity. Further muddying the waters when trying to understand and treat ASD, many previous studies show significant variability in findings.

Classified as: McGill Department of Psychiatry
Published on: 8 May 2019

On May 3, the announced the recent recipients of the NSERC Strategic Partnership Grants program. Six McGill-led projects in the Faculty of Engineering and one in the Faculty of Medicine are receiving more than $3.7 million to conduct research in collaboration with a supporting organization.

Classified as: Strategic Partnership Grants, NSERC, antimicrobial resistance, Li-ion batteries, Legionnaires' disease, Software-defined cloud radio access networks, autonomous Optical Networks, Predictive assessment of hydrogen diffusion and segregation in high-strength steels, science and technology
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Published on: 3 May 2019

New study of brain neurotransmitter receptor has implications for drug discovery

Surprisingly complex movements in an important neurotransmitter receptor may help explain the brain’s unpredictable response to drugs, according to a new study. New research from an international team, published this week in the journal Neuron, has revealed that the resting state of signaling proteins are much more dynamic than previously thought.

Classified as: neuroscience, Department of Pharmacology and Therapeutics
Published on: 30 Apr 2019

Imagine a computer 300,000 times faster than a PC, and with 67,000 times more storage space. Such is Béluga, a supercomputer now serving McGill, Québec, and Canadian researchers.

Classified as: supercomputer, Ï㽶ÊÓƵ, Calcul Québec
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Published on: 26 Apr 2019

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