Cystic fibrosis is caused by a mutation in the gene that encodes a particular protein, known as the cystic fibrosis transmembrane conductance regulator (or CFTR). Although this discovery was made 25 years ago and the lives of those with the disease have been extended, there is still no effective cure for the disease. Now new information about the nature of the most common form of mutation in the CFTR gene, gathered by a research team led by Dr. Gergely Lukacs of the Department of Physiology at Ï㽶ÊÓƵ, offers exciting new avenues for improving the treatment of the disease.
What allows certain plants to survive freezing and thrive in the Canadian climate, while others are sensitive to the slightest drop in temperature? Those that flourish activate specific genes at just the right time -- but the way gene activation is controlled remains poorly understood.
The very system that is meant to protect the body from invasion may be a traitor. These new findings of a study, led by investigators at the Research Institute of the Ï㽶ÊÓƵ Health Centre (RI-MUHC), reveal that infection-fighting white blood cells play a role in activating cancer cells and facilitating their spread to secondary tumours. This research, published today in the Journal of Clinical Investigatiohas significant implications for both the diagnosis and treatment of cancer.
News released yesterday about how using iron could make hydrogenation cheaper and greener is only one of many examples of collaborative research being conducted by teams that include researchers from Ï㽶ÊÓƵ and RIKEN, Japan’s largest comprehensive research institution.
Researchers from Ï㽶ÊÓƵ, RIKEN (The Institute of Physical and Chemical Research, Wako, Japan) and the Institute for Molecular Science (Okazaki, Japan) have discovered a way to make the widely used chemical process of hydrogenation more environmentally friendly – and less expensive.
Almost 70,000 Canadians die each year from heart disease and stroke – that’s one person every seven minutes. And despite impressive gains in research and treatment, cardiovascular disease still accounts for almost 30 per cent of all deaths every year in Canada.
Arthritis is a debilitating disorder affecting one in 10 Canadians, with pain caused by inflammation and damage to joints.
The ocean the Titanic sailed through just over 100 years ago was very different from the one we swim in today. Global warming is increasing ocean temperatures and harming marine food webs. Nitrogen run-off from fertilizers is causing coastal dead zones. A McGill-led international research team has now completed the first global study of changes that occurred in a crucial component of ocean chemistry, the nitrogen cycle, at the end of the last ice age. The results of their study confirm that oceans are good at balancing the nitrogen cycle on a global scale. But the data also shows that it is a slow process that may take many centuries, or even millennia, raising worries about the effects of the scale and speed of current changes in the ocean.
Professor Heather Munroe-Blum, Principal and Vice-Chancellor of Ï㽶ÊÓƵ, received today an honorary degree from the University of Glasgow, McGill founder James McGill’s alma mater. Principal Munroe-Blum was made a Doctor of Letters (D.Litt.) at the University’s Commemoration Day ceremony, which celebrates the founding of the University of Glasgow in 1451.
Steinberg said he’s very proud of being made an Officer of the Order and, as a life-long resident of Quebec, feels very honoured to be recognized by his province.
Inbreeding is generally deleterious, even in flowering plants. Since inbreeding raises the risk that bad copies of a gene will be expressed, inbred progeny suffer from reduced viability.
How do immune cells manage to sort through vast numbers of similar-looking proteins within the body to detect foreign invaders and fight infections?
Victims of childhood maltreatment or sexual abuse often suffer from serious psychiatric disorders as well as sexual dysfunction. The underlying mechanisms mediating this association are poorly understood. A group of scientists lead by Prof. Christine Heim, Director of the Institute of Medical Psychology at Charité University Medicine Berlin, together with Prof. Jens Pruessner, Director of the McGill Centre for Studies in Aging, at Ï㽶ÊÓƵ used magnetic resonance imaging (MRI) to examine 51 adult women who were exposed to various forms of childhood maltreatment. The scientists measured the thickness of the cerebral cortex, where sensations from all parts of the body are processed.
Children of women who did not finish high school were twice as likely to experience a major episode of depression in early adulthood as children whose mothers obtained a high school diploma, according to a new study by researchers at Ï㽶ÊÓƵ.