Ghrelin promotes conditioning to food-related odours
The holiday season is a hard one for anyone watching their weight. The sights and smells of food are hard to resist. One factor in this hunger response is a hormone found in the stomach that makes us more vulnerable to tasty food smells, encouraging overeating and obesity. New research on the hormone ghrelin was published on Dec. 4, 2018, led by Dr. Alain Dagher鈥檚 lab at the Montreal Neurological Institute and Hospital of 香蕉视频.
Reducing stigma may address cognitive impairment in this population
A new study has drawn a direct link between the amount of stigma men with HIV report experiencing and their scores on cognitive tests, measuring abilities such as memory and attention.
Concerns raised about efficacy of off-label use of already approved drugs
A new paper published by 香蕉视频 researchers in JAMA Internal Medicine suggests that some clinical trials may promote the use of ineffective and costly treatments. That鈥檚 the opposite of what clinical trials are aimed at, namely preventing ineffective and costly treatments from being taken up by physicians and patients.
Source: MUHC Newsroom
Source: Cell Metabolism
New research suggests that higher-level brain functions have a major role in losing weight. In a study among 24 participants at a weight-loss clinic, those who achieved greatest success in terms of weight loss demonstrated more activity in the brain regions of the lateral prefrontal cortex associated with self-control. The results of the study were published in听Cell Metabolism听on October 18.
Brain cancer begins in stem cells, targeting them may prevent tumour growth
Researchers at the Montreal Neurological Institute and Hospital (The Neuro) have found an exciting new way of treating brain cancer.
Late stage brain cancer cells are heterogeneous 鈥� they differ down to the molecular level. This makes developing treatments at this stage difficult, because a drug that may be effective against one cell may not be effective against another.
Researchers discover additional targets for existing drugs used to treat a specific melanoma
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A set of targeted cancer drugs, known as BRAF and MEK inhibitors, have proven to be beneficial for some metastatic melanoma patients whose tumours include a specific mutation in the BRAF gene, known as V600E. A recent study conducted in the lab of Dr. Peter Siegel at 香蕉视频鈥檚 Goodman Cancer Research Centre suggests that these same drugs may prove beneficial for a broader range of cancer patients.
The Consortium for Industrial Research and Innovation in Medical Technologies, , and the Healthy Brains for Healthy Lives (HBHL) initiative of 香蕉视频 are pleased to announce a joint agreement that will harmonize the process of developing research and innovation projects related to medical technologies.
Carriers at higher risk of developing neurodegenerative disease
A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital (The Neuro) has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson鈥檚 disease (PD), dementia with Lewy-Bodies (DLB) and multiple system atrophy (MSA).
To all members of the Faculty of Medicine,
Further to听last week鈥檚 update听on the McIntyre Medical Sciences Building, during which we confirmed the opening of the 5th and 6th floor amphitheatres and 2nd floor classrooms, we are pleased to report that the following additional areas will be opened as follows:
To all members of the Faculty of Medicine,
With the new academic year set to begin in earnest, I am pleased to report a great deal of progress has been made with respect to remediation efforts at the McIntyre Building following the July 13 fire. I take this opportunity to thank the University鈥檚 Project Review team who have taken over the reins from the Emergency Operations Committee and who continue their meticulous work to minimize disruptions to our community.
Please take note of the following updates:
Building Access:
When it comes to weight gain, the problem may be mostly in our heads, and our genes
Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.
To all members of the Faculty of Medicine,
One of the tightest bottlenecks in vascular tissue engineering is the lack of strength and elasticity of engineered vascular wall models caused by limited elastic fiber deposition. In this study, collagen gel-based scaffolds were cellularised with vascular smooth muscle cells (SMCs) and supplemented with human plasma fibronectin (FN), a known master organizer of several extracellular matrix (ECM) fiber systems.
